• br Discussion In this study we demonstrate

  2018-11-05

  

  Discussion In this study, we demonstrate that more than a quarter of AF patients have CKD, and that age, female sex, CHF, previous stroke/TIA and the occurrence of paroxysmal AF were significantly associated with CKD in AF patients. Second, we found a linear association between CrCl and TTR in AF

• While most HIV infected individuals

  2018-11-05

  

  While most HIV-1 infected individuals develop nAbs against their circulating variants and viruses escape this humoral pressure, there are potentially two important factors that explain why CXCR4-using variants do not evolve in everyone. First, CXCR4-utilizing viruses will not emerge if the circulati

• Conflicts of Interest br The paper

  2018-11-05

  

  Conflicts of Interest The paper by addresses important issues in understanding the heterogeneous pathogenetic pathways in Wilms tumors and also practical questions of how sensitive and specific is a tumor biopsy for identifying important genetic changes. Histopathologists are used to morphologic

• First are there characteristic sequential changes in circadi

  2018-11-05

  

  First, are there characteristic sequential changes in patupilone related to the exacerbation of BD symptoms? So far, studies about the disturbances of circadian rhythms related to BD have been almost entirely cross-sectional (Nurnberger et al., 2000; Wood et al., 2009). If we identify sequential ch

• br Materials and Methods br Results br Discussion Although

  2018-11-05

  

  Materials and Methods Results Discussion Although genome-wide association studies provide a systematic, powerful, and unbiased method for studying the common disease/common variant (CDCV) hypothesis of complex disorders such as schizophrenia, the identification of susceptibility loci for sc

• Clinical trials targeting multiple neoplasms

  2018-11-05

  

  Clinical trials targeting multiple neoplasms have been launched to assess the effects of autophagy inhibition in combination with radiation, conventional cytotoxic chemotherapies and targeted agents including DNA damaging agents, HDAC inhibitors, proteasome inhibitors, mitotic inhibitors, antiandrog

• Alzheimer s disease is the most common progressive

  2018-11-05

  

  Alzheimer\'s disease is the most common progressive neurodegenerative dementia and is characterized by the accumulation of plaques and intra-neuronal fibrillary tangles, where the former consists of beta-amyloid peptides (Aβ) that are highly insoluble and toxic (Querfurth and LaFerla, 2010), and the

• It is with much pride that I am able

  2018-11-05

  

  It is with much pride that I am able to write the foreword to our first issue of the (SAJCE) published by Elsevier. The Journal was originally published by the South African Institution of Chemical Engineers. I remember receiving copies of the journal by post in the late 1990s as an undergraduate s

• The availability of energy resources likely affects the

  2018-11-05

  

  The availability of energy resources likely affects the body’s ability to expend effort. One means by which energy is released is through glucose metabolism. Glucose utilization as reflected by plasma glucose levels was reduced during the 24h sleep deprivation period and was associated with decrease

• OSA is a common sleep disordered breathing characterized

  2018-11-05

  

  OSA is a common sleep disordered breathing, characterized by recurrent apneas (complete breathing cessation) or hypopneas (shallow breathing), upper airway constriction, hypoxemia, hypercapnia, autonomic activation, and EEG arousal and sleep fragmentation, leading to daytime fatigue and sleepiness [

• The limitations of our study include a relatively small samp

  2018-11-05

  

  The limitations of our study include a relatively small sample size and that serum samplings for inflammatory complement components and other inflammatory mediators were performed at one time point (before subjects went to bed). The serum levels of inflammatory molecules, e.g., IL-6, C-3, and C-4, e

• Prather in a recent study on

  2018-11-05

  

  Prather [14], in a recent study on 164 healthy subjects experimentally exposed to rhinovirus, observed through pulse actigraphy that those with fewer than six hours of sleep, before exposure, were four times more likely to become sick (9h), presented a risk of 1.39 (95%; 1.06–1.82) and 1.38 (95%; 1.

• The clinical definition of frailty remains controversial but

  2018-11-03

  

  The clinical definition of frailty remains controversial, but one validated measure is the Frailty Index, where frailty is the result of an accumulation of health deficits over time, and the severity of frailty can predict adverse health outcomes (Rockwood and Mitnitski, 2007). In the general popul

• The objective was to understand the diversity

  2018-11-03

  

  The objective was to understand the aromatase inhibitors of this organism across Europe and to get insight into the geographical and temporal evolution of the different genotypes. The diversity of P. jirovecii isolates responsible for PCP across different European countries (n=12) was investigated,

• br Data The information and results presented in this data

  2018-11-03

  

  Data The information and results presented in this data article are derived from the in vitro experiments for investigation of the arsenic responsive genes. We also provide in silico data on gene annotation that can be potentially useful for conducting microbial bioremediation of toxic metals.

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