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br Acknowledgement The authors Andrei G Simonassi and
2018-10-26

Acknowledgement The authors Andrei G Simonassi and Ronaldo A. Arraes thank the financial support from CNPq. Introduction In recent decades, surveys were published seeking explanations for an empirical verification of Zipf\'s law. Among the most important are the works of Rosen and Resnick (19
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br miRNAs are small non coding
2018-10-25

miRNAs are small non-coding RNAs affecting the expression of many genes and are regarded as crucial regulators involved in the fine-tuning of all cellular processes. Organ- and disease-specific miRNAs have been described. They are not only found within thymidylate synthase inhibitor but also in b
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br Introduction Advances in the treatment
2018-10-25

Introduction Advances in the treatment of HIV infection have dramatically reduced AIDS mortality and improved the quality of life of many people living with HIV (Palella et al., 1998). The initiation of ART results in a rapid drop in plasma viral load and in a substantial reduction in the number
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The use of NSC carriers has recently been
2018-10-25

The use of NSC carriers has recently been extended into the loading of adenoviruses. By allowing either the infection or replication only within cancer cells, the use of recently developed conditionally targeted or replicative adenoviruses (CRAds) has become an attractive modality for treatment. Thi
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The CDKN A gene locus encodes for p ARF p
2018-10-25

The CDKN2A gene locus encodes for p14ARF, p16INK4a, and the long non-coding RNA ANRIL, which negatively regulates p16INK4a. p16INK4a inhibits CDK4 and CDK6 activity, which regulate the RB-E2F axis and cell cycle progression (Nilsson and Landberg, 2006; Jin et al., 1995; Jacobs et al., 1999; Abella e
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br Identification of phosphorylation sites by
2018-10-25

Identification of phosphorylation sites by NanoLC–MS/MS To determine phosphorylation sites of the identified phosphoprotein, we isolated total proteins from C101LAC and CO39 at 12h post-inoculation and mixed them in a 1:1 (w/w total protein) ratio. Protein sphingosine-1-phosphate was performed a
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br Experimental design materials and methods The synthesis
2018-10-25

Experimental design, materials and methods The synthesis was carried out as described previously [1]. “Krokodil extract” samples were obtained by the treatment of 4mL of crude “krokodil” with NaOH 20% (m/v) until alkalization, followed by extraction with ethyl acetate. The organic phases were gat
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br Experimental design materials and methods br Acknowledgme
2018-10-25

Experimental design, materials and methods Acknowledgments The present study took place in the context of the program ׳GOSHOMICS׳, under the action COOPERATION 2009 (SYNERGASIA 2009), financed by the European Regional Development Fund and National Resources, project code: 09SYN-23-990. Data
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Moreover while previous developmental neuroimaging studies h
2018-10-25

Moreover, while previous developmental neuroimaging studies have found a shift from prefrontal regions in children to parietal regions in adults (Ansari et al., 2005; Cantlon et al., 2009; Holloway and Ansari, 2010; Kaufmann et al., 2005, 2006), the present study did not reveal a negative correlatio
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There are million medical doctors
2018-10-25

There are ∼8 million medical doctors in the world and the ratio of those to the population by country varies from 1 to 440 per 100,000 people. Although this ratio is 164 physicians per every 100,000 people for the UK, it is only 1.1 for Rwanda. Although telemedicine and teledermatology applications
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br Analytical models br Contours of three
2018-10-25

Analytical models Contours of three typical detonation waves The configuration of EFP warhead with a wave shaper is shown in Fig. 2. As shown in Fig. 2, two propagation paths for the detonation wave are created after the initiator initiates the subsidiary charge, where one path climbs the wav
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One of the key issues with
2018-10-25

One of the key issues with IEDs, be they enkephalin deployed on land or at sea, is that they are “fairly easy to build but difficult to detect and clear” [2]. However, the damage that can potentially be caused by a relatively inexpensive UWIED to multi-million dollar surface vessels and submarines
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Janet Malcolm Gedisa Barcelona br La propuesta del doctor Cl
2018-10-25

Janet Malcolm: . Gedisa, Barcelona, 2003. La propuesta del doctor Claudio Stern, contenida en el presente libro, cuestiona, duda, critica y construye un enfoque alternativo, lo que aplica bradykinin receptor antagonist un extenso esfuerzo de investigación, analizando resultados que plantean enorm
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Esta conjunci n entre un orden social arcaico
2018-10-25

Esta conjunción entre un orden social arcaico y el capo de las drogas y su territorio se recrea en de Yuri , una de las contribuciones más interesantes GDC0068 la creciente literatura del norte. Lo que suele entenderse como narcoliteratura suele tender a adquirir la forma de historias de aventuras
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Polymethacrylates are synthetic cationic and anionic polymer
2018-10-25

Polymethacrylates are synthetic cationic and anionic polymers of dimethylaminoethyl methacrylates, methacrylic acid, and methacrylic BMS-650032 esters in varying ratios. Several types are commercially available and may be obtained as the dry powder, aqueous dispersion, organic solution [1]. The mos
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